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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 28653-1-AP (same clone as 28653-1-PBS)

    WB analysis using 28653-1-AP (same clone as 28653-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28653-1-AP (VPS33B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28653-1-AP (VPS33B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28653-1-AP (VPS33B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

VPS33B Polyclonal antibody, PBS Only

VPS33B Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28653-1-PBS

Print datasheet

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

28653-1-PBS targets VPS33B in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen VPS33B fusion protein Ag29886 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name vacuolar protein sorting 33 homolog B (yeast)
Synonyms
Calculated Molecular Weight 617 aa, 71 kDa
Observed Molecular Weight65 kDa
GenBank Accession NumberBC016445
Gene Symbol VPS33B
Gene ID (NCBI) 26276
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H267
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

VPS33B, a homolog of yeast class C vacuolar protein sorting (vps) protein Vps33p, belongs to the STXBP/unc-18/SEC1 family. It may play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. VPS33B mediates phagolysosomal fusion in macrophages (PMID: 18474358). Defects in VPS33B account for most cases of arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome, which is a multisystem disorder associated with abnormalities in polarized liver and kidney cells (PMID: 20190753).