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×
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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 28653-1-AP (same clone as 28653-1-PBS)

    WB analysis using 28653-1-AP (same clone as 28653-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28653-1-AP (VPS33B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28653-1-AP (VPS33B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    IHC staining of mouse kidney using 28653-1-AP (same clone as 28653-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 28653-1-AP (VPS33B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28653-1-PBS in a different storage buffer formulation.

VPS33B Polyclonal antibody, PBS Only

VPS33B Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 28653-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

28653-1-PBS targets VPS33B in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 VPS33B fusion protein Ag29886 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 vacuolar protein sorting 33 homolog B (yeast)
别名
计算分子量 617 aa, 71 kDa
观测分子量65 kDa
GenBank蛋白编号BC016445
基因名称 VPS33B
Gene ID (NCBI) 26276
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H267
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

VPS33B, a homolog of yeast class C vacuolar protein sorting (vps) protein Vps33p, belongs to the STXBP/unc-18/SEC1 family. It may play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. VPS33B mediates phagolysosomal fusion in macrophages (PMID: 18474358). Defects in VPS33B account for most cases of arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome, which is a multisystem disorder associated with abnormalities in polarized liver and kidney cells (PMID: 20190753).