• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

WFS1 Polyclonal antibody, PBS Only

WFS1 Polyclonal Antibody for IHC, IF/ICC, IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF/ICC, IF-P, Indirect ELISA

Conjugate

Unconjugated

Cat no : 26995-1-PBS

Print datasheet

Synonyms

验证数据展示

  • IHC staining of rat brain using 26995-1-AP (same clone as 26995-1-PBS)

    IHC staining of rat brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 26995-1-AP (WFS1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WFS1 antibody included
  • IHC staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IHC staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 26995-1-AP (WFS1 antibody) at dilution of 1:400 (under 4x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WFS1 antibody included
  • IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of HepG2 using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy WFS1 Ready-To-Use IHC Kit. WFS1 primary antibody included.

产品信息

26995-1-PBS targets WFS1 in IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, IF/ICC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen WFS1 fusion protein Ag25724 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name Wolfram syndrome 1 (wolframin)
Synonyms
Calculated Molecular Weight 890 aa, 100 kDa
GenBank Accession NumberBC030130
Gene Symbol WFS1
Gene ID (NCBI) 7466
RRIDAB_2880717
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO76024
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Wolfram syndrome protein (WFS1), also called wolframin, is a transmembrane protein, which is located primarily in the endoplasmic reticulum and its expression is induced in response to ER stress, partially through transcriptional activation. ER localization suggests that WFS1 protein has physiological functions in membrane trafficking, secretion, processing and/or regulation of ER calcium homeostasis. It is ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations of the WFS1 gene are responsible for two hereditary diseases, autosomal recessive Wolfram syndrome and autosomal dominant low frequency sensorineural hearing loss.