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验证数据展示

  • IHC staining of rat brain using 26995-1-AP (same clone as 26995-1-PBS)

    IHC staining of rat brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 26995-1-AP (WFS1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WFS1 antibody included
  • IHC staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IHC staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 26995-1-AP (WFS1 antibody) at dilution of 1:400 (under 4x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with WFS1 antibody included
  • IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of mouse brain using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 26995-1-AP (same clone as 26995-1-PBS)

    IF Staining of HepG2 using 26995-1-AP (same clone as 26995-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using WFS1 antibody (26995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26995-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

WFS1 Polyclonal antibody, PBS Only

WFS1 Polyclonal Antibody for IHC, IF/ICC, IF-P, Indirect ELISA
Cat No. 26995-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, IF/ICC, IF-P, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy WFS1 Ready-To-Use IHC Kit. WFS1 primary antibody included.

产品信息

26995-1-PBS targets WFS1 in IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 WFS1 fusion protein Ag25724 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Wolfram syndrome 1 (wolframin)
别名
计算分子量 890 aa, 100 kDa
GenBank蛋白编号BC030130
基因名称 WFS1
Gene ID (NCBI) 7466
RRIDAB_2880717
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO76024
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Wolfram syndrome protein (WFS1), also called wolframin, is a transmembrane protein, which is located primarily in the endoplasmic reticulum and its expression is induced in response to ER stress, partially through transcriptional activation. ER localization suggests that WFS1 protein has physiological functions in membrane trafficking, secretion, processing and/or regulation of ER calcium homeostasis. It is ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations of the WFS1 gene are responsible for two hereditary diseases, autosomal recessive Wolfram syndrome and autosomal dominant low frequency sensorineural hearing loss.