XBP1S-specific Recombinant antibody

XBP1S-specific Uni-rAbTM Recombinant Antibody for IHC, ELISA
Cat No. 83959-6-RR

产品说明书

CloneNo. 241004C10

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, ELISA

XBP1, 241004C10, Tax-responsive element-binding protein 5, TREB-5, X box binding protein 1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive IHC detected inmouse liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83959-6-RR targets XBP1S-specific in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原 XBP1S-specific fusion protein Ag21703 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 X-box binding protein 1
别名 XBP1, 241004C10, Tax-responsive element-binding protein 5, TREB-5, X box binding protein 1
计算分子量 261 aa, 29 kDa
GenBank蛋白编号BC000938
基因名称 XBP1
Gene ID (NCBI) 7494
RRIDAB_3671538
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP17861
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

XBP1, also named as XBP2, belongs to the bZIP family. The X-box-binding protein-1 (XBP1) is a transcriptional regulator of the ER stress response that lies downstream of inositol-requiring enzyme 1 (IRE1α) activation (PMID: 14559994). XBP1 localizes in the nucleus. As a transcription factor, it is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The unspliced XBP1U isoform is composed of 261 amino acid residues, and the spliced XBP1S isoform is composed of 376 amino acid residues.

实验方案

Product Specific Protocols
IHC protocol for XBP1S-specific antibody 83959-6-RRDownload protocol
Standard Protocols
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