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YAP-TEAD-IN-1 acetate

YAP-TEAD-IN-1 acetate 是一种有效的、竞争性的 YAP-TEAD 相互作用抑制剂，IC50 为 25 nM。

CAS号

TP2160L1

分子式

C95H148ClN23O23S2

主要靶点

YAP

仅限科研使用

Cat No : CM15847

Print datasheet

Synonyms

YAP-TEAD-IN-1 acetate (1659305-78-8 Free base)

验证数据展示

  • CAS No.: TP2160L1

    YAP-TEAD-IN-1 acetate
    CAS#: TP2160L1

产品信息

YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.

CAS号 TP2160L1
分子式 C95H148ClN23O23S2
主要靶点 YAP
主要通路 干细胞
分子量 2079.92
纯度 99.57%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 YAP-TEAD-IN-1 acetate (1659305-78-8 Free base)

体外活性

YAP-TEAD-IN-1 acetate (2 μM) shows a higher binding affinity to TEAD1 (Kd = 15 nM) than YAP (50-171) (Kd = 40 nM)[1].

参考文献

1.Zhang Z, et al. Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.ACS Med Chem Lett. 2014 Jul 14;5(9):993-8.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2