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YEATS2 Polyclonal antibody

YEATS2 Polyclonal Antibody for WB, IP, IHC, ELISA
Cat No. 24717-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

WB, IP, IHC, ELISA

KIAA1197, YEATS domain containing 2, YEATS2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inJurkat cells
Positive IP detected inJurkat cells
Positive IHC detected inhuman cervical cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:200-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24717-1-AP targets YEATS2 in WB, IHC, IP, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, IHC, ELISA Application Description
文献引用应用WB, IHC, IP
经测试反应性 human
文献引用反应性human, mouse
免疫原 YEATS2 fusion protein Ag20134 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 YEATS domain containing 2
别名 KIAA1197, YEATS domain containing 2, YEATS2
计算分子量 1422 aa, 151 kDa
观测分子量 151 kDa
GenBank蛋白编号BC150273
基因名称 YEATS2
Gene ID (NCBI) 55689
RRIDAB_2879686
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9ULM3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

YEATS domain containing 2 (YEATS2) protein is a scaffolding subunit of the ATAC complex. Studies have shown that YEATS2 is a selective histone crotonylation reader and is related to histone acetylation. In addition, YEATS2 is associated with the progression of various tumors. Overexpression of YEATS2 promotes the proliferation and migration of pancreatic cancer cells. YEATS2 has been reported to be associated with the progression of non-small-cell lung cancer through histone acetylation.

实验方案

Product Specific Protocols
WB protocol for YEATS2 antibody 24717-1-APDownload protocol
IHC protocol for YEATS2 antibody 24717-1-APDownload protocol
IP protocol for YEATS2 antibody 24717-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Nat Commun

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.

Authors - Wenyi Mi
  • KD Validated
humanWB,IHC,IP

Cell Biol Toxicol

YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival.

Authors - Hao Sheng
  • KD Validated
humanWB,IHC

J Cell Physiol

YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.

Authors - Zhirui Zeng
  • KD Validated
humanWB

Signal Transduct Target Ther

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma.

Authors - Yiyi Xi
mouseWB,IHC

Phytomedicine

Cinobufacini retards progression of pancreatic ductal adenocarcinoma through targeting YEATS2/TAK1/NF-κB axis

Authors - Tian Lan
humanWB

Cancers (Basel)

Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway

Authors - Xin Liu
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