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验证数据展示

  • WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

    WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

    human kidney tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

YY2 Monoclonal antibody, PBS Only

YY2 Monoclonal Antibody for WB, ELISA
Cat No. 66839-1-PBS

产品说明书

CloneNo. 1C11A7

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, ELISA

别名

Transcription factor YY2, Yin and yang 2, YY 2, YY2, YY2 transcription factor, Zinc finger protein 631, ZNF631

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66839-1-PBS targets YY2 in WB, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human
免疫原 YY2 fusion protein Ag25373 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 YY2 transcription factor
别名 Transcription factor YY2, Yin and yang 2, YY 2, YY2, YY2 transcription factor, Zinc finger protein 631, ZNF631
计算分子量 372 aa, 46 kDa
观测分子量 46 kDa
GenBank蛋白编号BC137217
基因名称 YY2
Gene ID (NCBI) 404281
RRIDAB_2882182
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO15391
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

YY2 (Yin-Yang 2) encodes a zinc finger transcription factor similarity to the well-characterized YY1 that locating to nucleus. Both proteins recognize an identical DNA-binding motifs with a high homologous Zinc Finger region, and these transcription factors can act as activators or repressors when bound to DNA (PMID:26350623). It is reported that YY2 is placental mammal-specific and is absent in marsupial and non-mammalian vertebrate species (PMID:16377127). YYs are play an important role in multiple developmental processes , such as implantation, cell differentiation, X inactivation, imprinting and organogenesis (PMID:27191592). YY2 is expressed in kindey, liver, spleen and testicle but not in the colon (PMID:15087442). A 41kDa band could be detected.