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YY2 Monoclonal antibody, PBS Only

YY2 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1C11A7

Cat no : 66839-1-PBS

Print datasheet

Synonyms

Transcription factor YY2, Yin and yang 2, YY 2, YY2, YY2 transcription factor, Zinc finger protein 631, ZNF631

验证数据展示

  • WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

    WB analysis of human kidney using 66839-1-Ig (same clone as 66839-1-PBS)

    human kidney tissue were subjected to SDS PAGE followed by western blot with 66839-1-Ig (YY2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66839-1-PBS in a different storage buffer formulation.

产品信息

66839-1-PBS targets YY2 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human
Immunogen YY2 fusion protein Ag25373 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name YY2 transcription factor
Synonyms Transcription factor YY2, Yin and yang 2, YY 2, YY2, YY2 transcription factor, Zinc finger protein 631, ZNF631
Calculated Molecular Weight 372 aa, 46 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberBC137217
Gene Symbol YY2
Gene ID (NCBI) 404281
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO15391
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

YY2 (Yin-Yang 2) encodes a zinc finger transcription factor similarity to the well-characterized YY1 that locating to nucleus. Both proteins recognize an identical DNA-binding motifs with a high homologous Zinc Finger region, and these transcription factors can act as activators or repressors when bound to DNA (PMID:26350623). It is reported that YY2 is placental mammal-specific and is absent in marsupial and non-mammalian vertebrate species (PMID:16377127). YYs are play an important role in multiple developmental processes , such as implantation, cell differentiation, X inactivation, imprinting and organogenesis (PMID:27191592). YY2 is expressed in kindey, liver, spleen and testicle but not in the colon (PMID:15087442). A 41kDa band could be detected.