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Conjugate
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Conjugate
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ZNF154 Polyclonal antibody, PBS Only

ZNF154 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, monkey

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22161-1-PBS

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Synonyms

验证数据展示

  • WB analysis of COS-7 using 22161-1-AP (same clone as 22161-1-PBS)

    WB analysis of COS-7 using 22161-1-AP (same clone as 22161-1-PBS)

    COS-7 cells were subjected to SDS PAGE followed by western blot with 22161-1-AP (ZNF154 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22161-1-PBS in a different storage buffer formulation.

产品信息

22161-1-PBS targets ZNF154 in WB, Indirect ELISA applications and shows reactivity with human, monkey samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, monkey
Immunogen ZNF154 fusion protein Ag17812 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name zinc finger protein 154
Synonyms
Calculated Molecular Weight 437 aa, 50 kDa
Observed Molecular Weight 55-60 kDa
GenBank Accession NumberBC152404
Gene Symbol ZNF154
Gene ID (NCBI) 7710
RRIDAB_2879012
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13106
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, The hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. The magnitude and reproducibility of the ZNF154 hypermethylation signal across five solid tumor types reinforces the potential of this site as a biomarker for circulating tumor DNA (ctDNA)(PMID: 26857064 ). The calculated molecular weight of ZNF154 is 50 kDa, but the modified ZNF154 protein is about 55-60 kDa.