ZNF750 Polyclonal antibody
ZNF750 Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IHC, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive IHC detected in | human oesophagus cancer tissue, human skin tissue, human skin cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 2 publications below |
| IHC | See 1 publications below |
产品信息
The immunogen of 21752-1-AP is ZNF750 Fusion Protein expressed in E. coli.
| Tested Applications | IHC, ELISA Application Description |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Immunogen | ZNF750 fusion protein Ag16116 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | zinc finger protein 750 |
| Synonyms | Protein ZNF750, Zfp750, zinc finger protein 750, ZNF750 |
| Calculated Molecular Weight | 723 aa, 77 kDa |
| Observed Molecular Weight | 70-77 kDa |
| GenBank Accession Number | BC109037 |
| Gene Symbol | ZNF750 |
| Gene ID (NCBI) | 79755 |
| RRID | AB_10863125 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q32MQ0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ZNF750 is a novel nuclear protein highly expressed in differentiated skin keratinocytes. Mutation of ZNF750 is linked with familial psoriasis. Recently ZNF was found to be significantly mutated in esophageal squamous cell carcinoma (ESCC). Expression of ZNF750 is decreased in ESCC compared to the normal tissue.
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for ZNF750 antibody 21752-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Int J Cancer Identification of calmodulin-like protein 5 as tumor-suppressor gene silenced during early stage of carcinogenesis in squamous cell carcinoma of uterine cervix. | ||
Oncol Lett Differentiation-related zinc finger protein 750 suppresses cell growth in esophageal squamous cell carcinoma. | ||
Cell Death Discov TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750 |
