验证数据展示
产品信息
67262-1-PBS targets ZnT3 in WB, Indirect ELISA applications and shows reactivity with Human, pig, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, pig, rat |
免疫原 | ZnT3 fusion protein Ag10735 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | solute carrier family 30 (zinc transporter), member 3 |
别名 | SLC30A3, Zinc transporter 3, ZnT 3, ZNT3 |
计算分子量 | 388 aa, 42 kDa |
观测分子量 | 38-40 kDa |
GenBank蛋白编号 | BC028358 |
基因名称 | ZnT3 |
Gene ID (NCBI) | 7781 |
RRID | AB_2882533 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q99726 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ZnT3, encoded by SLC30A3, is a member of SLC30A family which is zinc transporter sequestrating cytosolic zinc into intracellular compartments or effluxing zinc to the extracellular space. Excessive zinc level can cause neuron apoptosis and lead to cognitive impairments. Znt3 facilitates the transport and storage of zinc in synaptic vesicles. Abnormal ZnT3 expression has been linked to some neurodegenerative disorders.