Lamin A/C Polyclonal antibody

Lamin A/C Polyclonal Antibody for FC, IF, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (1)





Cat No : 10298-1-AP

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70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, lamin A, lamin A/C, LDP1, LFP, LGMD1B, LMN1, LMNA, LMNC, Prelamin A/C, PRO1, progerin


Positive WB detected inNIH/3T3 cells, HEK-293 cells, C6 cells, A375 cells, mouse ovary tissue, HUVEC cells, SKOV-3 cells
Positive IP detected inA375 cells
Positive IF detected inHepG2 cells, HeLa cells
Positive FC detected inHEK-293T cells


Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery


10298-1-AP targets Lamin A/C in WB, IP, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications FC, IF, IP, WB,ELISA
Cited Applications IF, WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, duck
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Lamin A/C fusion protein Ag0408
Full Name lamin A/C
Calculated molecular weight 65 kDa
Observed molecular weight 65 kDa, 70 kDa
GenBank accession numberBC003162
Gene symbol LMNA
Gene ID (NCBI) 4000
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.


Lamin A/C is also named as LMNA, or LMN1. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. The lack of lamin A/C can be as a novel marker for undifferentiated embryonic stem cells and lamin A/C expression is as an early indicator of differentiation (PMID: 16179429). Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 74 kDa, 65 kDa, 70 kDa and 64 kDa. This antibody can recognize 4 isoforms of Lamin A/C.


Product Specific Protocols
WB protocol for Lamin A/C antibody 10298-1-APDownload protocol
IF protocol for Lamin A/C antibody 10298-1-APDownload protocol
IP protocol for Lamin A/C antibody 10298-1-APDownload protocol
FC protocol for Lamin A/C antibody 10298-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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