Nectin-4/PVRL4 Recombinant antibody, PBS Only (Detector)

Nectin-4/PVRL4 Uni-rAbTM Recombinant Antibody for IF/ICC, FC, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, FC, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240009F2

Cat no : 83223-4-PBS

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Synonyms

Nectin-4, PVRL4, Nectin cell adhesion molecule 4, nectin 4, LNIR



Planning an IHC experiment? We recommend our IHCeasy Nectin-4/PVRL4 Ready-To-Use IHC Kit. Nectin-4/PVRL4 primary antibody included.

产品信息

83223-4-PBS targets Nectin-4/PVRL4 as part of a matched antibody pair:

MP00147-1: 83223-1-PBS capture and 83223-4-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications IF/ICC, FC, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Affinity
KD=2.28 x 10-10M
KOff=2.98 x 10-5M
KOn=2.62 x 105M
Full Name poliovirus receptor-related 4
Synonyms Nectin-4, PVRL4, Nectin cell adhesion molecule 4, nectin 4, LNIR
Calculated Molecular Weight 510 aa, 55 kDa
GenBank Accession NumberBC010423
Gene Symbol Nectin-4
Gene ID (NCBI) 81607
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ96NY8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Nectin-4, or PVRL4, belongs to the family of cell adhesion molecules that regulate the formation of adherence functions in epithelial cells through the AF-6 afadin scaffold molecule. Nectin-4 is reported as a histological and serological marker for breast carcinoma. Nectin-4 can be detected as a soluble form of 43 kDa and a transmembrane form of 66 kDa (PMID: 15784625).