Cdkn2a/p16INK4a Polyclonal antibody

p16INK4a Polyclonal Antibody for WB, ELISA
Cat No. 28416-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat

应用

WB, ELISA

Cdkn2a, p16-INK4a, p16-INK4, p16(INK4a), p16

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inNIH/3T3 cells, Neuro-2a cells, RAW 264.7 cells, C6 cells, mouse uterus tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28416-1-AP targets p16INK4a in WB, ELISA applications and shows reactivity with mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 mouse, rat
免疫原 p16INK4a fusion protein Ag28927 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cyclin-dependent kinase inhibitor 2A
别名 Cdkn2a, p16-INK4a, p16-INK4, p16(INK4a), p16
计算分子量 18 kDa
观测分子量18 kDa
GenBank蛋白编号NM_001040654
基因名称 Cdkn2a
Gene ID (NCBI) 12578
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP51480
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cdkn2a (cyclin-dependent kinase inhibitor 2a) is a cell cycle regulating gene encoding alternate proteins, p16Ink4a and p19Arf, that arrest the G1 phase through CDK4/6 inhibition. As they are tumor suppressors, p16Ink4a and p19Arf can be targeted for treatment of various cancers, including melanoma, cervical, and esophageal cancers.

实验方案

Product Specific Protocols
WB protocol for p16INK4a antibody 28416-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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