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  • Featured Product
  • KD/KO Validated

peroxiredoxin 2 Monoclonal antibody, PBS Only

peroxiredoxin 2 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3H6C4

Cat no : 60202-1-PBS

Print datasheet

Synonyms

PRDX2, Peroxiredoxin-2, NKEF-B, NKEFB, Natural killer cell-enhancing factor B

验证数据展示

  • WB analysis using 60202-1-Ig (same clone as 60202-1-PBS)

    WB analysis using 60202-1-Ig (same clone as 60202-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60202-1-Ig (peroxiredoxin 2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60202-1-PBS in a different storage buffer formulation.

  • WB analysis of HepG2 using 60202-1-Ig (same clone as 60202-1-PBS)

    WB analysis of HepG2 using 60202-1-Ig (same clone as 60202-1-PBS)

    WB result of peroxiredoxin 2 antibody (60202-1-Ig; 1:30000; incubated at room temperature for 1.5 hours) with sh-Control and sh-peroxiredoxin 2 transfected HepG2 cells. This data was developed using the same antibody clone with 60202-1-PBS in a different storage buffer formulation.

  • IHC staining of human testis using 60202-1-Ig (same clone as 60202-1-PBS)

    IHC staining of human testis using 60202-1-Ig (same clone as 60202-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 60202-1-Ig(peroxiredoxin 2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60202-1-PBS in a different storage buffer formulation.

  • IHC staining of human testis using 60202-1-Ig (same clone as 60202-1-PBS)

    IHC staining of human testis using 60202-1-Ig (same clone as 60202-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human testis using 60202-1-Ig(peroxiredoxin 2 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60202-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 60202-1-Ig (same clone as 60202-1-PBS)

    IF Staining of MCF-7 using 60202-1-Ig (same clone as 60202-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using peroxiredoxin 2 antibody (60202-1-Ig, Clone: 3H6C4 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 60202-1-PBS in a different storage buffer formulation.

产品信息

60202-1-PBS targets peroxiredoxin 2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen peroxiredoxin 2 fusion protein Ag0835 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name peroxiredoxin 2
Synonyms PRDX2, Peroxiredoxin-2, NKEF-B, NKEFB, Natural killer cell-enhancing factor B
Calculated Molecular Weight 22 kDa
Observed Molecular Weight 22 kDa
GenBank Accession NumberBC003022
Gene Symbol peroxiredoxin 2
Gene ID (NCBI) 7001
RRIDAB_10918978
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP32119
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PRDX2, also named as TSA, PRP, NKEFB and TDPX1, belongs to the ahpC/TSA family. It is known to act as an antioxidant enzyme whose main function is H2O2 reduction in cells. PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. It may play an important role in eliminating peroxides generated during metabolism. PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. PRDX2 actions may be related to the expression of NFKB and IKB.(PMID:21248284)