Phospho-AKT (Tyr315) Monoclonal antibody

Phospho-Akt (Tyr315) Monoclonal Antibody for ELISA
Cat No. 60072-1-Ig

产品说明书

CloneNo. 5C4D12

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse and More (1)

应用

ELISA and More (2)

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy AKT Ready-To-Use IHC Kit. AKT primary antibody included.

产品信息

60072-1-Ig targets Phospho-Akt (Tyr315) in WB, IF, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse
文献引用反应性human, rat
免疫原 Phospho Peptide 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 v-akt murine thymoma viral oncogene homolog 1
别名
计算分子量 56 kDa
观测分子量 62 kDa
GenBank蛋白编号NM_005163
基因名称 AKT1
Gene ID (NCBI) 207
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP31749
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protein kinase B (PKB/Akt) has been well established as an important signaling intermediate, and its deregulation has been implicated in the development of human cancer and diabetes(PMID:12176337). Akt, also known as protein kinase B (PKB), is a serine/threonine kinase activated downstream of class I phosphatidylinositol 3-kinase (PI3K) and various receptors. It has emerged as the key regulator for many signal transduction pathways, modulating multiple processes such as cell survival, proliferation, growth, angiogenesis, and glucose metabolism(PMID:16139227). Its deregulation has been implicated in the development of human cancer and diabetes(PMID:12176337).

发表文章

SpeciesApplicationTitle
humanWB

Sci Rep

TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.

Authors - Fengqin Dong
ratWB

Neuropharmacology

Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.

Authors - Nan Wang
humanWB

Mar Drugs

11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways.

Authors - Jen-Jie Lin
humanWB

PLoS One

Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.

Authors - Yuan Tian
humanWB

Apoptosis

SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.

Authors - Lei Gao
humanWB

Biochim Biophys Acta

Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation.

Authors - Jiawei Guan
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