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验证数据展示

  • WB analysis of COLO 320 using 60243-1-Ig (same clone as 60243-1-PBS)

    WB analysis of COLO 320 using 60243-1-Ig (same clone as 60243-1-PBS)

    COLO 320 cells were subjected to SDS PAGE followed by western blot with 60243-1-Ig (CDX2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60243-1-PBS in a different storage buffer formulation.

  • IF Staining of Caco-2 using 60243-1-Ig (same clone as 60243-1-PBS)

    IF Staining of Caco-2 using 60243-1-Ig (same clone as 60243-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Caco-2 cells using CDX2 antibody (60243-1-Ig, Clone: 5A4E6 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60243-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50121-1

    Cytometric bead array standard curve of MP50121-1

    Cytometric bead array standard curve of MP50121-1, CDX2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60243-1-PBS. Detection antibody: 60243-3-PBS. Standard:Ag17644. Range: 0.098-100 ng/mL.

  • Featured Product
  • KD/KO验证

CDX2 Monoclonal antibody, PBS Only (Capture)

CDX2 Monoclonal Antibody for WB, IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 60243-1-PBS

产品说明书

CloneNo. 5A4E6

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

WB, IF/ICC, Cytometric bead array, Indirect ELISA

别名

CDX-2, CDX 3, Caudal-type homeobox protein 2, Caudal type homeobox protein 2, Caudal type homeobox 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CDX2 Ready-To-Use IHC Kit. CDX2 primary antibody included.

产品信息

60243-1-PBS targets CDX2 as part of a matched antibody pair:

MP50121-1: 60243-1-PBS capture and 60243-3-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, IF/ICC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human, pig
免疫原 CDX2 fusion protein Ag17644 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 caudal type homeobox 2
别名 CDX-2, CDX 3, Caudal-type homeobox protein 2, Caudal type homeobox protein 2, Caudal type homeobox 2
计算分子量 313 aa, 34 kDa
观测分子量 33-40 kDa
GenBank蛋白编号BC014461
基因名称 CDX2
Gene ID (NCBI) 1045
RRIDAB_2881365
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99626
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.