验证数据展示
经过测试的应用
| Positive WB detected in | pig retina tissue, mouse retina tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
66494-1-Ig targets NR2E3 in WB, ELISA applications and shows reactivity with Pig, Mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | Pig, Mouse |
| 免疫原 | NR2E3 fusion protein Ag5831 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | nuclear receptor subfamily 2, group E, member 3 |
| 别名 | ESCS, NR2E3, PNR, rd7, RNR, RP37 |
| 计算分子量 | 45 kDa |
| 观测分子量 | 45-50 kDa |
| GenBank蛋白编号 | BC041421 |
| 基因名称 | NR2E3 |
| Gene ID (NCBI) | 10002 |
| RRID | AB_2881859 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q9Y5X4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for NR2E3 antibody 66494-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
