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NR2E3 Monoclonal antibody, PBS Only

NR2E3 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Pig, Mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G1D9

Cat no : 66494-1-PBS

Print datasheet

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37

验证数据展示

  • WB analysis of pig retina using 66494-1-Ig (same clone as 66494-1-PBS)

    WB analysis of pig retina using 66494-1-Ig (same clone as 66494-1-PBS)

    pig retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66494-1-PBS in a different storage buffer formulation.

产品信息

66494-1-PBS targets NR2E3 in WB, Indirect ELISA applications and shows reactivity with Pig, Mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Pig, Mouse
Immunogen NR2E3 fusion protein Ag5831 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name nuclear receptor subfamily 2, group E, member 3
Synonyms ESCS, NR2E3, PNR, rd7, RNR, RP37
Calculated Molecular Weight 45 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC041421
Gene Symbol NR2E3
Gene ID (NCBI) 10002
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y5X4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]