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ASGR2 Monoclonal antibody

ASGR2 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A5C12

Cat no : 66831-1-Ig

Print datasheet

Synonyms

ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2

验证数据展示

  • WB analysis of SMMC-7721 using 66831-1-Ig

    WB analysis of SMMC-7721 using 66831-1-Ig

    SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 66831-1-Ig (ASGR2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inSMMC-7721 cells, HSC-T6 cells
Planning an IHC experiment? We recommend our IHCeasy ASGR2 Ready-To-Use IHC Kit. ASGR2 primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66831-1-Ig targets ASGR2 in WB, ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, rat
Immunogen ASGR2 fusion protein Ag2037 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name asialoglycoprotein receptor 2
Synonyms ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 36 kDa
GenBank Accession NumberBC017251
Gene Symbol ASGR2
Gene ID (NCBI) 433
RRIDAB_2882174
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP07307
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

实验方案

Product Specific Protocols
WB protocol for ASGR2 antibody 66831-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols