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验证数据展示

  • WB analysis of SMMC-7721 using 66831-1-Ig (same clone as 66831-1-PBS)

    WB analysis of SMMC-7721 using 66831-1-Ig (same clone as 66831-1-PBS)

    SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 66831-1-Ig (ASGR2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66831-1-PBS in a different storage buffer formulation.

ASGR2 Monoclonal antibody, PBS Only

ASGR2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66831-1-PBS

产品说明书

CloneNo. 2A5C12

宿主/亚型

Mouse / IgG2a

种属反应性

Human, rat

应用

WB, Indirect ELISA

别名

ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy ASGR2 Ready-To-Use IHC Kit. ASGR2 primary antibody included.

产品信息

66831-1-PBS targets ASGR2 in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 ASGR2 fusion protein Ag2037 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 asialoglycoprotein receptor 2
别名 ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2
计算分子量 39 kDa
观测分子量 36 kDa
GenBank蛋白编号BC017251
基因名称 ASGR2
Gene ID (NCBI) 433
RRIDAB_2882174
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP07307
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.