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验证数据展示

  • WB analysis of SMMC-7721 using 66831-1-Ig

    WB analysis of SMMC-7721 using 66831-1-Ig

    SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 66831-1-Ig (ASGR2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

ASGR2 Monoclonal antibody

ASGR2 Monoclonal Antibody for WB, ELISA
Cat No. 66831-1-Ig

产品说明书

CloneNo. 2A5C12

宿主/亚型

Mouse / IgG2a

种属反应性

Human, rat

应用

WB, ELISA

别名

ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inSMMC-7721 cells, HSC-T6 cells
Planning an IHC experiment? We recommend our IHCeasy ASGR2 Ready-To-Use IHC Kit. ASGR2 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

66831-1-Ig targets ASGR2 in WB, ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 Human, rat
免疫原 ASGR2 fusion protein Ag2037 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 asialoglycoprotein receptor 2
别名 ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2
计算分子量 39 kDa
观测分子量 36 kDa
GenBank蛋白编号BC017251
基因名称 ASGR2
Gene ID (NCBI) 433
RRIDAB_2882174
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP07307
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

实验方案

Product Specific Protocols
WB protocol for ASGR2 antibody 66831-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols