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MVK Monoclonal antibody

MVK Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2F1D3

Cat no : 67820-1-Ig

Print datasheet

Synonyms

FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK

验证数据展示

  • WB analysis using 67820-1-Ig

    WB analysis using 67820-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inLNCaP cells, U2OS cells, HepG2 cells, Jurkat cells, K-562 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67820-1-Ig targets MVK in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human
Immunogen MVK fusion protein Ag28887 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name mevalonate kinase
Synonyms FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK
Calculated Molecular Weight 396 aa, 42 kDa
Observed Molecular Weight 42 kDa
GenBank Accession NumberBC016140
Gene Symbol MVK
Gene ID (NCBI) 4598
RRIDAB_2918583
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ03426
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.

实验方案

Product Specific Protocols
WB protocol for MVK antibody 67820-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols