验证数据展示
产品信息
67820-1-PBS targets MVK in WB, Indirect ELISA applications and shows reactivity with Human samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human |
| Immunogen | MVK fusion protein Ag28887 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | mevalonate kinase |
| Synonyms | FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK |
| Calculated Molecular Weight | 396 aa, 42 kDa |
| Observed Molecular Weight | 42 kDa |
| GenBank Accession Number | BC016140 |
| Gene Symbol | MVK |
| Gene ID (NCBI) | 4598 |
| RRID | AB_2918583 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q03426 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.
