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  • Featured Product
  • KD/KO Validated

ATL3 Monoclonal antibody, PBS Only (Detector)

ATL3 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, rabbit

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E7C4

Cat no : 68516-1-PBS

Print datasheet

Synonyms

EC:3.6.5.-, Atlastin-3, Atlastin 3, 2E7C4

验证数据展示

  • WB analysis using 68516-1-Ig (same clone as 68516-1-PBS)

    WB analysis using 68516-1-Ig (same clone as 68516-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68516-1-Ig (ATL3 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68516-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 68516-1-Ig (same clone as 68516-1-PBS)

    WB analysis of Jurkat using 68516-1-Ig (same clone as 68516-1-PBS)

    WB result of ATL3 antibody (68516-1-Ig; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-ATL3 transfected Jurkat cells. This data was developed using the same antibody clone with 68516-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50703-1

    Cytometric bead array standard curve of MP50703-1

    Cytometric bead array standard curve of MP50703-1, ATL3 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68516-2-PBS. Detection antibody: 68516-1-PBS. Standard:Ag10248. Range: 0.781-100 ng/mL.

产品信息

68516-1-PBS targets ATL3 as part of a matched antibody pair:

MP50703-1: 68516-2-PBS capture and 68516-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, rabbit
Immunogen ATL3 fusion protein Ag10248 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name atlastin GTPase 3
Synonyms EC:3.6.5.-, Atlastin-3, Atlastin 3, 2E7C4
Calculated Molecular Weight 541 aa, 61 kDa
Observed Molecular Weight 61 kDa
GenBank Accession NumberBC077727
Gene Symbol ATL3
Gene ID (NCBI) 25923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ6DD88
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF.