• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • Neutralization experiment of NeutraKine® IFN Alpha 2A using 69008-1-Ig (same clone as 69008-1-PBS)

    Neutralization experiment of NeutraKine® IFN Alpha 2A using 69008-1-Ig (same clone as 69008-1-PBS)

    Recombinant human IFN alpha 2A (Cat.NO. HZ-1066) inhibits the growth of TF-1 cell line (human erythroleukemic cell line) in a dose-dependent manner (blue curve, refer to bottom X-left Y). The activity of human IFN alpha 2A (100 ng/mL HZ-1066) is neutralized by mouse anti-human IFN alpha 2A monoclonal antibody 69008-1-Ig at serial dose (red curve, refer to top X-right Y). The ND50 is typically 300-500 ng/mL. This data was developed using the same antibody clone with 69008-1-PBS in a different storage buffer formulation.

  • Sandwich ELISA standard curve of MP50005-1

    Sandwich ELISA standard curve of MP50005-1

    Sandwich ELISA standard curve of MP50005-1, IFNA2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 69008-1-PBS. Detection antibody: 68665-1-PBS. Standard: HZ-1066. Range: 7.8-500 pg/mL.

NeutraKine® IFN Alpha 2A Monoclonal antibody, PBS Only (Capture)

NeutraKine® IFN Alpha 2A Monoclonal Antibody for Neutralization, Sandwich ELISA, Indirect ELISA, Sample test
Cat No. 69008-1-PBS

产品说明书

CloneNo. 2H8G1

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

Neutralization, Sandwich ELISA, Indirect ELISA, Sample test

别名

IFN alpha 2, IFNA2, 2H8G1, IFN alpha 2A, IFN alpha2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

69008-1-PBS targets NeutraKine® IFN Alpha 2A as part of a matched antibody pair:

MP50005-1: 69008-1-PBS capture and 68665-1-PBS detection (validated in Sandwich ELISA)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 Neutralization, Sandwich ELISA, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 human Humankine IFN Alpha 2A protein HZ-1066 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interferon, alpha 2
别名 IFN alpha 2, IFNA2, 2H8G1, IFN alpha 2A, IFN alpha2
基因名称 IFN alpha2
Gene ID (NCBI) 3440
RRIDAB_2882926
偶联类型 Unconjugated
形式 Lyophilized Powder
纯化方式Protein G purification
储存缓冲液 PBS only , pH 7.3
内毒素<0.1 EU/μg
复溶This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
稳定性与储存Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

背景介绍

Interferon alpha 2 is a type 1 interferon. Interferon alpha 2 is secreted by virus-infected cells and inhibits other cells from further infection. Recombinant human interferon alpha 2 has been approved for therapeutic application in a range of human oncological and viral diseases. Three Interferon alpha 2 subvariants (2A, 2B, 2C) differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (PMID: 25982860; 10672347; 1694761).

This antibody can be used to neutralize the bioactivity of Interferon alpha 2.