INPP5E Recombinant antibody
INPP5E Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
1E7
验证数据展示
经过测试的应用
Positive IF/ICC detected in | Starvation treated hTERT-RPE1 cells |
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
82689-3-RR targets INPP5E in IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | human |
Immunogen | INPP5E fusion protein Ag30305 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | inositol polyphosphate-5-phosphatase, 72 kDa |
Synonyms | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, Inositol polyphosphate-5-phosphatase E, EC:3.1.3.86, EC:3.1.3.36, 72 kDa inositol polyphosphate 5-phosphatase |
Calculated Molecular Weight | 644 aa, 70 kDa |
Observed Molecular Weight | 64-66 kDa |
GenBank Accession Number | BC028032 |
Gene Symbol | INPP5E |
Gene ID (NCBI) | 56623 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9NRR6 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
INPP5E(72 kDa inositol polyphosphate 5-phosphatase) converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2.In mouse, highest protein expression was in brain, heart, and testis, with lower expression in thymus and lung, and very little expression in kidney, spleen, and liver(PMID:10764818). Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1) and mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS)(PMID:19668215). It has 2 isoforms with the molecular mass of 66 kDa and 70 kDa.
实验方案
Product Specific Protocols | |
---|---|
IF protocol for INPP5E antibody 82689-3-RR | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |