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FTCD Recombinant antibody, PBS Only (Capture)

FTCD Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240654G9

Cat no : 83664-2-PBS

Print datasheet

Synonyms

Glutamate formiminotransferase, Glutamate formimidoyltransferase, Formiminotransferase-cyclodeaminase, Formimidoyltransferase-cyclodeaminase, Formimidoyltetrahydrofolate cyclodeaminase

验证数据展示

  • WB analysis using 83664-2-RR (same clone as 83664-2-PBS)

    WB analysis using 83664-2-RR (same clone as 83664-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83664-2-RR (FTCD antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83664-2-PBS in a different storage buffer formulation.

  • FC experiment of HepG2 using 83664-2-RR (same clone as 83664-2-PBS)

    FC experiment of HepG2 using 83664-2-RR (same clone as 83664-2-PBS)

    1x10^6 HepG2 cells were intracellularly stained with 0.25 ug FTCD Recombinant antibody (83664-2-RR, Clone:240654G9) and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.25 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 83664-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00636-1

    Cytometric bead array standard curve of MP00636-1

    Cytometric bead array standard curve of MP00636-1, FTCD Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83664-2-PBS. Detection antibody: 83664-3-PBS. Standard: Ag16646. Range: 0.625-80 ng/mL.

  • Affinity and Kinetic Characterization of 83664-2-RR

    Affinity and Kinetic Characterization of 83664-2-RR

    Biolayer interferometry (BLl) kinetic assays of 83664-2-RR against Human FTCD were performed. The affinity constant is 6.37 nM.

Planning an IHC experiment? We recommend our IHCeasy FTCD Ready-To-Use IHC Kit. FTCD primary antibody included.

产品信息

83664-2-PBS targets FTCD as part of a matched antibody pair:

MP00636-1: 83664-2-PBS capture and 83664-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen FTCD fusion protein Ag16646 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name formiminotransferase cyclodeaminase
Synonyms Glutamate formiminotransferase, Glutamate formimidoyltransferase, Formiminotransferase-cyclodeaminase, Formimidoyltransferase-cyclodeaminase, Formimidoyltetrahydrofolate cyclodeaminase
Calculated Molecular Weight 541 aa, 59 kDa
Observed Molecular Weight58 kDa
GenBank Accession NumberBC136395
Gene Symbol FTCD
Gene ID (NCBI) 10841
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO95954
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FTCD (formimidoyltransferase cyclodeaminase) is critical for the catabolism of histidine, a . This process is one-carbon units that can enter the one-carbon/folate cycle, which provides methyl groups for arsenic metabolism (PMID: 30893314). In addition, FTCD could serve as a predictive and prognostic marker for patients with HCC (PMID: 37675273).