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CD117/c-Kit Recombinant antibody, PBS Only (Capture/Detector)

CD117/c-Kit Uni-rAbTM Recombinant Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241313D5

Cat no : 84259-1-PBS

Print datasheet

Synonyms

CD117, KIT, EC:2.7.10.1, c-Kit, C Kit

验证数据展示

  • Cytometric bead array standard curve of MP01171-2

    Cytometric bead array standard curve of MP01171-2

    Cytometric bead array standard curve of MP01171-2, CD117/c-Kit Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84259-3-PBS. Detection antibody: 84259-1-PBS. Standard: RP02323. Range: 0.156-20 ng/mL.

  • Cytometric bead array standard curve of MP01171-3

    Cytometric bead array standard curve of MP01171-3

    Cytometric bead array standard curve of MP01171-3, CD117/c-Kit Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84259-1-PBS. Detection antibody: 84259-2-PBS. Standard: RP02323. Range: 0.156-20 ng/mL.

Planning an IHC experiment? We recommend our IHCeasy CD117/c-kit Ready-To-Use IHC Kit. CD117/c-kit primary antibody included.

产品信息

84259-1-PBS targets CD117/c-Kit as part of a matched antibody pair:

MP01171-2: 84259-3-PBS capture and 84259-1-PBS detection (validated in Cytometric bead array)

MP01171-3: 84259-1-PBS capture and 84259-2-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Synonyms CD117, KIT, EC:2.7.10.1, c-Kit, C Kit
Calculated Molecular Weight 976 aa, 110 kDa
GenBank Accession NumberBC071593
Gene Symbol CD117
Gene ID (NCBI) 3815
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP10721
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early hemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).