验证数据展示
经过测试的应用
| Positive WB detected in | Raji cells, HeLa cells, A431 cells |
Planning an IHC experiment? We recommend our IHCeasy IMPDH1 Ready-To-Use IHC Kit. IMPDH1 primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
84913-1-RR targets IMPDH1 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | IMPDH1 fusion protein Ag17473 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | IMP (inosine monophosphate) dehydrogenase 1 |
| 别名 | IMPDH 1, IMPD1, IMPD 1, IMP dehydrogenase 1, EC:1.1.1.205 |
| 计算分子量 | 563 aa, 60 kDa |
| 观测分子量 | 53-60 kDa |
| GenBank蛋白编号 | BC033622 |
| 基因名称 | IMPDH1 |
| Gene ID (NCBI) | 3614 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P20839 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IMPDH1(Inosine-5'-monophosphate dehydrogenase 1) is also named as IMPD1, IMP dehydrogenase 1 and belongs to the IMPDH/GMPR family. It catalyzes the rate limiting step of de novo guanine synthesis and an important target for the development of drugs with both chemotherapeutic and immunosuppressive activity. It may also have a role in the development of malignancy and the growth progression of some tumors. This protein has some isoforms produced by alternative splicing with the molecular mass of 53-65 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for IMPDH1 antibody 84913-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |