Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody

Fas/CD95 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

241229C11

Cat no : 98135-1-RR

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Synonyms

Fas, CD95, TNFR6, APT1, APO 1



经过测试的应用

Positive FC detected inmouse thymocytes

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98135-1-RR targets Fas/CD95 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name Fas (TNF receptor superfamily member 6)
Synonyms Fas, CD95, TNFR6, APT1, APO 1
Calculated Molecular Weight37kDa
GenBank Accession NumberNM_007987.2
Gene Symbol Fas/CD95
Gene ID (NCBI) 14102
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP25446
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.

实验方案

Product Specific Protocols
FC protocol for Fas/CD95 antibody 98135-1-RRDownload protocol
Standard Protocols
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