• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody, PBS Only

Fas/CD95 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

241229C11

Cat no : 98135-1-PBS

Print datasheet

Synonyms

Fas, CD95, TNFR6, APT1, APO 1

验证数据展示

  • FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody (98135-1-RR, Clone: 241229C11) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD8a (53-6.7) (APC-65069, Clone: 53-6.7). Cells were not fixed. This data was developed using the same antibody clone with 98135-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody (98135-1-RR, Clone: 241229C11) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98135-1-PBS in a different storage buffer formulation.

产品信息

98135-1-PBS targets Fas/CD95 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name Fas (TNF receptor superfamily member 6)
Synonyms Fas, CD95, TNFR6, APT1, APO 1
Calculated Molecular Weight37kDa
GenBank Accession NumberNM_007987.2
Gene Symbol Fas/CD95
Gene ID (NCBI) 14102
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP25446
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.