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验证数据展示

  • FC experiment of human PBMCs using 98157-1-RR

    FC experiment of human PBMCs using 98157-1-RR

    1x10^6 untreated or PMA and ionomycin treated human PBMCs were surface stained with 0.25 ug Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody (98157-1-RR, Clone: 241280B12) and PE-conjugated Goat Anti-Rabbit IgG. Cells were co-stained with CoraLite® Plus 647 Anti-Human CD8. Cells were not fixed.

  • FC experiment of human PBMCs using 98157-1-RR

    FC experiment of human PBMCs using 98157-1-RR

    1x10^6 PMA and ionomycin treated human PBMCs were surface stained with 0.25 ug Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody (98157-1-RR, Clone: 241280B12) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. 1x10^6 untreated human PBMCs were surface stained with 0.25 ug Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody (98157-1-RR, Clone: 241280B12) and PE-conjugated Goat Anti-Rabbit IgG (dashed, black). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98157-1-RR

    Affinity and Kinetic Characterization of 98157-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98157-1-RR against Human CRTAM/CD355 were performed. The affinity constant is 0.449 nM.

Anti-Human CRTAM/CD355 Rabbit Recombinant Antibody

CRTAM/CD355 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98157-1-RR

产品说明书

CloneNo. 241280B12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CRTAM, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule, CD355, 241280B12

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive FC detected inPMA and ionomycin treated human PBMCs

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98157-1-RR targets CRTAM/CD355 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cytotoxic and regulatory T cell molecule
别名 CRTAM, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule, CD355, 241280B12
计算分子量45 kDa
GenBank蛋白编号NM_019604.4
基因名称 CRTAM
Gene ID (NCBI) 56253
RRIDAB_3672300
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO95727-1
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223).

实验方案

Product Specific Protocols
FC protocol for CRTAM/CD355 antibody 98157-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols