Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody

Integrin alpha-5/CD49e Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241685D4

Cat no : 98171-1-RR

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Synonyms

Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e



经过测试的应用

Positive FC detected inhuman PBMCs
Planning an IHC experiment? We recommend our IHCeasy ITGA5 Ready-To-Use IHC Kit. ITGA5 primary antibody included.

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98171-1-RR targets Integrin alpha-5/CD49e in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Synonyms Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e
Calculated Molecular Weight 115 kDa
GenBank Accession NumberBC008786
Gene Symbol Integrin alpha 5
Gene ID (NCBI) 3678
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP08648
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha-5 (ITGA5, also known as CD49e), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).

实验方案

Product Specific Protocols
FC protocol for Integrin alpha-5/CD49e antibody 98171-1-RRDownload protocol
Standard Protocols
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