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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody (98171-1-RR, Clone: 241685D4) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98171-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody (98171-1-RR, Clone: 241685D4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98171-1-PBS in a different storage buffer formulation.

Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody, PBS Only

Integrin alpha-5/CD49e Uni-rAbTM Recombinant Antibody for FC
Cat No. 98171-1-PBS

产品说明书

CloneNo. 241685D4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy ITGA5 Ready-To-Use IHC Kit. ITGA5 primary antibody included.

产品信息

98171-1-PBS targets Integrin alpha-5/CD49e in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
别名 Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e
计算分子量 115 kDa
GenBank蛋白编号BC008786
基因名称 Integrin alpha 5
Gene ID (NCBI) 3678
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP08648
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha-5 (ITGA5, also known as CD49e), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).