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Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody, PBS Only

Integrin alpha-5/CD49e Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241685D4

Cat no : 98171-1-PBS

Print datasheet

Synonyms

Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e

验证数据展示

  • FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody (98171-1-RR, Clone: 241685D4) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98171-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    FC experiment of human PBMCs using 98171-1-RR (same clone as 98171-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Integrin alpha-5/CD49e Rabbit Recombinant Antibody (98171-1-RR, Clone: 241685D4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98171-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy ITGA5 Ready-To-Use IHC Kit. ITGA5 primary antibody included.

产品信息

98171-1-PBS targets Integrin alpha-5/CD49e in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Synonyms Integrin Alpha-5, ITGA5, Integrin alpha-5 heavy chain, FNRA, CD49e
Calculated Molecular Weight 115 kDa
GenBank Accession NumberBC008786
Gene Symbol Integrin alpha 5
Gene ID (NCBI) 3678
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP08648
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha-5 (ITGA5, also known as CD49e), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).