验证数据展示
产品信息
60153-1-PBS targets ABCD1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | ABCD1 fusion protein Ag12757 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | ATP-binding cassette, sub-family D (ALD), member 1 |
Synonyms | ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN |
Calculated Molecular Weight | 745 aa, 83 kDa |
Observed Molecular Weight | 75 kDa |
GenBank Accession Number | BC025358 |
Gene Symbol | ABCD1 |
Gene ID (NCBI) | 215 |
RRID | AB_10640436 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P33897 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.