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  • Featured Product
  • KD/KO Validated

ABCD1 Monoclonal antibody, PBS Only

ABCD1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H8E5

Cat No : 60153-1-PBS

Print datasheet

Synonyms

ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN

验证数据展示

  • WB analysis of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

    WB analysis of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

    WB result of ABCD1 antibody (60153-1-Ig, 1:1000) with si-Control and si-ABCD1 transfected HeLa cells. This data was developed using the same antibody clone with 60153-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

    IF Staining of HeLa using 60153-1-Ig (same clone as 60153-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using ABCD1 antibody (60153-1-Ig, Clone: 1H8E5 ) at dilution of 1:100 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).DAPI (blue). This data was developed using the same antibody clone with 60153-1-PBS in a different storage buffer formulation.

产品信息

60153-1-PBS targets ABCD1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen ABCD1 fusion protein Ag12757 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name ATP-binding cassette, sub-family D (ALD), member 1
Synonyms ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN
Calculated Molecular Weight 745 aa, 83 kDa
Observed Molecular Weight 75 kDa
GenBank Accession NumberBC025358
Gene Symbol ABCD1
Gene ID (NCBI) 215
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP33897
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.