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ABCD1 Monoclonal antibody
ABCD1 Monoclonal Antibody for WB, IF/ICC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
WB, IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
1H8E5
验证数据展示
经过测试的应用
Positive WB detected in | HeLa cells |
Positive IF/ICC detected in | HeLa cells |
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
60153-1-Ig targets ABCD1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF/ICC, ELISA Application Description |
Tested Reactivity | human |
Immunogen | ABCD1 fusion protein Ag12757 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | ATP-binding cassette, sub-family D (ALD), member 1 |
Synonyms | ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN |
Calculated Molecular Weight | 745 aa, 83 kDa |
Observed Molecular Weight | 75 kDa |
GenBank Accession Number | BC025358 |
Gene Symbol | ABCD1 |
Gene ID (NCBI) | 215 |
RRID | AB_10640436 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P33897 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.
实验方案
Product Specific Protocols | |
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WB protocol for ABCD1 antibody 60153-1-Ig | Download protocol |
IF protocol for ABCD1 antibody 60153-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |