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ABCD1 Monoclonal antibody

ABCD1 Monoclonal Antibody for IF, WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IF, WB, ELISA

Conjugate

Unconjugated

CloneNo.

1H8E5

Cat No : 60153-1-Ig

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Synonyms

ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN



经过测试的应用

Positive WB detected inHeLa cells
Positive IF detected inHeLa cells
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60153-1-Ig targets ABCD1 in WB, IF, ELISA applications and shows reactivity with human samples.

Tested Applications IF, WB, ELISA
Tested Reactivity human
Immunogen ABCD1 fusion protein Ag12757 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name ATP-binding cassette, sub-family D (ALD), member 1
Synonyms ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN
Calculated Molecular Weight 745 aa, 83 kDa
Observed Molecular Weight 75 kDa
GenBank Accession NumberBC025358
Gene Symbol ABCD1
Gene ID (NCBI) 215
RRIDAB_10640436
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP33897
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.

实验方案

Product Specific Protocols
WB protocol for ABCD1 antibody 60153-1-IgDownload protocol
IF protocol for ABCD1 antibody 60153-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols