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ACVR1B Recombinant antibody, PBS Only

ACVR1B Recombinant Antibody for IF, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

IF, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230260E12

Cat No : 83026-5-PBS

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Synonyms

activin A receptor, type IB, Activin receptor like kinase 4, Activin receptor type 1B, Activin receptor type IB, ACTR IB, ACTRIB, ACVR1B, ACVRLK4, ALK 4, ALK4, SKR2

验证数据展示

  • IF Staining of NIH/3T3 using 83026-5-RR (same clone as 83026-5-PBS)

    IF Staining of NIH/3T3 using 83026-5-RR (same clone as 83026-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed NIH/3T3 cells using ACVR1B antibody (83026-5-RR, Clone: 230260E12 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83026-5-PBS in a different storage buffer formulation.

  • Affinity experiments of 83026-5-RR

    Affinity experiments of 83026-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83026-5-RR against Human ACVR1B were performed. The affinity constant is 16.1 nM.

产品信息

83026-5-PBS targets ACVR1B in IF, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications IF, Indirect ELISA Application Description
Tested Reactivity Human, mouse
Immunogen ACVR1B fusion protein Ag0129 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name activin A receptor, type IB
Synonyms activin A receptor, type IB, Activin receptor like kinase 4, Activin receptor type 1B, Activin receptor type IB, ACTR IB, ACTRIB, ACVR1B, ACVRLK4, ALK 4, ALK4, SKR2
Calculated Molecular Weight 57 kDa
GenBank Accession NumberBC000254
Gene Symbol ACVR1B
Gene ID (NCBI) 91
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP36896
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

ACVR1B (ALK4, activin A receptor type 1B) is a transforming growth factor-beta (TGF-beta) superfamily member (PMID: 37020544). A potential role for ACVR1B in regulating muscle mass is that it is part of the transforming growth factor b (TGFb) pathway regulating myostatin (PMID: 21063444).