ACVRL1 Recombinant antibody

ACVRL1 Recombinant Antibody for WB, ELISA
Cat No. 84421-3-RR

产品说明书

CloneNo. 241686H2

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHUVEC cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84421-3-RR targets ACVRL1 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 activin A receptor type II-like 1
别名 ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1
计算分子量 56 kDa
观测分子量63 kDa
GenBank蛋白编号BC042637
基因名称 ACVRL1
Gene ID (NCBI) 94
RRIDAB_3671949
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP37023
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2.

实验方案

Product Specific Protocols
WB protocol for ACVRL1 antibody 84421-3-RRDownload protocol
Standard Protocols
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