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验证数据展示

  • WB analysis of HUVEC using 84421-3-RR

    WB analysis of HUVEC using 84421-3-RR

    HUVEC cells were subjected to SDS PAGE followed by western blot with 84421-3-RR (ACVRL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

ACVRL1 Recombinant antibody

ACVRL1 Recombinant Antibody for WB, ELISA
Cat No. 84421-3-RR

Print datasheet

CloneNo. 241686H2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size: 

-/ -

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经过测试的应用

Positive WB detected inHUVEC cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84421-3-RR targets ACVRL1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen FusionProtein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name activin A receptor type II-like 1
Synonyms ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1
Calculated Molecular Weight 56 kDa
Observed Molecular Weight63 kDa
GenBank Accession NumberBC042637
Gene Symbol ACVRL1
Gene ID (NCBI) 94
RRIDAB_3671949
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP37023
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2.

实验方案

Product Specific Protocols
WB protocol for ACVRL1 antibody 84421-3-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols