验证数据展示
产品信息
68113-1-PBS targets ADAM8 in WB, FC, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Applications | WB, FC, Indirect ELISA Application Description |
Tested Reactivity | human, pig |
Immunogen | ADAM8 fusion protein Ag17262 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | ADAM metallopeptidase domain 8 |
Synonyms | MS2, EC:3.4.24.-, Disintegrin and metalloproteinase domain-containing protein 8, Cell surface antigen MS2, CD156a |
Calculated Molecular Weight | 824 aa, 89 kDa |
Observed Molecular Weight | 90 kDa |
GenBank Accession Number | BC115404 |
Gene Symbol | ADAM8 |
Gene ID (NCBI) | 101 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P78325 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ADAM8 is a type I transmembrane (TM) glycoprotein consisting of an N-terminal prodomain, followed by a metalloproteinase-, disintegrin (DIS)-, cysteine-rich-, epidermal growth factor (EGF)-like- and TM domain and a cytoplasmic tail. Expression levels of ADAM8 in normal tissue are typically low and limited to a few distinct cell types in the lymphatic organs as components of the immune system, the central nervous system, bone, and the lung. This antibody can be used to detect endogenous ADAM8 with an apparent molecular weight of 90 kDa (the calculated MW ). ADAM8 also can be detectable as a band with a molecular weight (MW) of 98 kDa, slightly larger than the calculated MW (90 kDa) (PMID:11050116).