验证数据展示
产品信息
67764-1-PBS targets ADARB1 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat |
免疫原 | ADARB1 fusion protein Ag17852 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | adenosine deaminase, RNA-specific, B1 (RED1 homolog rat) |
别名 | ADAR2, ADAR2a, ADAR2a L1, ADAR2a L2, ADAR2a L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, ADARB1, DRABA2, DRADA2, dsRNA adenosine deaminase, RED1, RNA editing deaminase 1, RNA editing enzyme 1 |
计算分子量 | 741 aa, 81 kDa |
观测分子量 | 70 kDa, 80 kDa |
GenBank蛋白编号 | BC065545 |
基因名称 | ADARB1 |
Gene ID (NCBI) | 104 |
RRID | AB_2918531 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P78563 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ADARB1 (Double-stranded RNA-specific editase 1) is also named as ADAR2, DRADA2, RED1 and belongs to the ADAR family. It catalyses the deamination of adenosine to inosine at the GluR2 Q/R site in the pre-mRNA encoding the critical subunit of AMPA receptors. This protein has some isoforms with the molecular weight from 77 kDa to 81 kDa and 7 kDa, but it can be detected a very strong band at 50 kDa in addition to a predicted band at 75 kDa as the result of western blot, while ADARB1 has several alternative splice variants (PMID:23103828).