验证数据展示
Planning an IHC experiment? We recommend our IHCeasy ADH1C Ready-To-Use IHC Kit. ADH1C primary antibody included.
产品信息
84546-1-PBS targets ADH1C in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 | ADH1C fusion protein Ag13528 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | alcohol dehydrogenase 1C (class I), gamma polypeptide |
| 别名 | EC:1.1.1.1, ADH3, 241623C3 |
| 计算分子量 | 375 aa, 40 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC062476 |
| 基因名称 | ADH1C |
| Gene ID (NCBI) | 126 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P00326 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Alcohol dehydrogenase 1C(ADH1C), also known as ADH3, is an alcohol dehydrogenase that can catalyze ethanol oxidation to metabolite acetaldehyde. According to THE HUMAN PROTEIN ATLAS database, ADH1C locates mainly to the cytosol and plasma membrane. Genetic polymorphism of the ADH1C gene (ADH1C*1 allele) is associated with various human cancers, such as gastric cancer, oral cancer and CRC, for it encodes an alcohol dehydrogenase producing 2.5 times more acetaldehyde.(PMID: 35300114)