ADRB2 Recombinant antibody
ADRB2 Uni-rAbTM Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
240186C9
验证数据展示
经过测试的应用
Positive IF/ICC detected in | A431 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of 83317-5-RR is ADRB2 Fusion Protein expressed in E. coli.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | ADRB2 fusion protein Ag3715 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | adrenergic, beta-2-, receptor, surface |
Synonyms | ADRB2, ADRB2R, ADRBR, B2AR, BAR, Beta 2 adrenergic receptor, Beta 2 adrenoceptor, Beta 2 adrenoreceptor, BETA2AR |
Calculated Molecular Weight | 46 kDa |
GenBank Accession Number | BC012481 |
Gene Symbol | ADRB2 |
Gene ID (NCBI) | 154 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P07550 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Beta-2 adrenergic receptor (ADRB2), a member of the G protein-coupled receptor (GPCR) family, binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. ADRB2 is directly linked to one of its final effectors, the class C L-type Ca2+ channel, Cav1.2 (PMID: 11441182). This receptor-channel complex also contains a G protein, an adenylyl cyclase, cyclic adenosine monophosphate-dependent protein kinase (PKA), and a counteracting phosphatase, PP2A. Different polymorphic forms, point mutations, and/or downregulation of the gene of ADRB2 are associated with nocturnal asthma, obesity, and type 2 diabetes.
实验方案
Product Specific Protocols | |
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IF protocol for ADRB2 antibody 83317-5-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |