验证数据展示
产品信息
60340-1-PBS targets Perilipin-2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | Perilipin-2 fusion protein Ag7643 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | adipose differentiation-related protein |
别名 | ADRP/Perilipin-2, ADRP/Perilipin 2, ADRP, ADFP, Perilipin 2 |
计算分子量 | 48 kDa |
观测分子量 | 47-52 kDa |
GenBank蛋白编号 | BC005127 |
基因名称 | Perilipin-2 |
Gene ID (NCBI) | 123 |
RRID | AB_2881449 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q99541 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ADRP (adipocyte differentiation related protein) also known as ADFP, adipophilin, or perilipin-2, is a member of PAT family which is responsible for the transportation of lipids and the formation of lipid droplets. ADRP is localized on the surface of lipid droplets in a variety of tissues and cell lines. ADRP is not detected in undifferentiated cells but increases rapidly to high levels when adipocyte precursors differentiate into adipocytes. Anti-ADRP antibody is a reliable and sensitive marker for lipid droplet. Enhanced expression of ADRP is linked to diseases with abnormal lipid storage, including hepatic steatosis, atherosclerosis and diabetes. Immunohistochemistry of ADRP may facilitate histomorphological diagnosis of these diseases.