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AEBP2 Monoclonal antibody, PBS Only

AEBP2 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, pig

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

7H2B11

Cat No : 66141-1-PBS

Print datasheet

Synonyms

AE binding protein 2, AEBP2, Zinc finger protein AEBP2

验证数据展示

  • WB analysis of HeLa using 66141-1-Ig (same clone as 66141-1-PBS)

    WB analysis of HeLa using 66141-1-Ig (same clone as 66141-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 66141-1-Ig (AEBP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66141-1-PBS in a different storage buffer formulation.

产品信息

66141-1-PBS targets AEBP2 in WB, ELISA applications and shows reactivity with human, pig samples.

Tested Applications WB,ELISA Application Description
Tested Reactivity human, pig
Immunogen AEBP2 fusion protein Ag17905 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name AE binding protein 2
Synonyms AE binding protein 2, AEBP2, Zinc finger protein AEBP2
Calculated Molecular Weight 33 kDa, 54 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC015624
Gene Symbol AEBP2
Gene ID (NCBI) 121536
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ6ZN18
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

AEBP2 belongs to the AEBP2/jing C2H2-type zinc-finger family. It is a DNA-binding transcriptional repressor. AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. (PMID:19293275) The antibody recognizes adult-specific larger form (52 kDa) and the embryo-specific smaller form (31 kDa).