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AGGF1 Recombinant antibody, PBS Only

AGGF1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242264E9

Cat no : 84715-3-PBS

Print datasheet

Synonyms

HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7, Angiogenic factor VG5Q

验证数据展示

  • WB analysis using 84715-3-RR (same clone as 84715-3-PBS)

    WB analysis using 84715-3-RR (same clone as 84715-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84715-3-RR (AGGF1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84715-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84715-3-RR

    Affinity and Kinetic Characterization of 84715-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84715-3-RR against Human AGGF1 were performed. The affinity constant is below 1 pM.

产品信息

84715-3-PBS targets AGGF1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen AGGF1 fusion protein Ag2497 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name angiogenic factor with G patch and FHA domains 1
Synonyms HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7, Angiogenic factor VG5Q
Calculated Molecular Weight 714 aa, 81 kDa
Observed Molecular Weight 84-100 kDa
GenBank Accession NumberBC029382
Gene Symbol AGGF1
Gene ID (NCBI) 55109
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8N302
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.