验证数据展示
产品信息
84715-3-PBS targets AGGF1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | AGGF1 fusion protein Ag2497 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | angiogenic factor with G patch and FHA domains 1 |
| Synonyms | HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7, Angiogenic factor VG5Q |
| Calculated Molecular Weight | 714 aa, 81 kDa |
| Observed Molecular Weight | 84-100 kDa |
| GenBank Accession Number | BC029382 |
| Gene Symbol | AGGF1 |
| Gene ID (NCBI) | 55109 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q8N302 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.