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AHR Polyclonal antibody, PBS Only

AHR Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 30242-1-PBS

Print datasheet

Synonyms

Class E basic helix-loop-helix protein 76, bHLHe76, Ah receptor

验证数据展示

  • WB analysis using 30242-1-AP (same clone as 30242-1-PBS)

    WB analysis using 30242-1-AP (same clone as 30242-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30242-1-AP (AHR antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30242-1-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 30242-1-AP (same clone as 30242-1-PBS)

    IHC staining of human ovary cancer using 30242-1-AP (same clone as 30242-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 30242-1-AP (AHR antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30242-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with AHR antibody included
  • IHC staining of human ovary cancer using 30242-1-AP (same clone as 30242-1-PBS)

    IHC staining of human ovary cancer using 30242-1-AP (same clone as 30242-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 30242-1-AP (AHR antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30242-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with AHR antibody included
Planning an IHC experiment? We recommend our IHCeasy AHR Ready-To-Use IHC Kit. AHR primary antibody included.

产品信息

30242-1-PBS targets AHR in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen AHR fusion protein Ag32335 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name aryl hydrocarbon receptor
Synonyms Class E basic helix-loop-helix protein 76, bHLHe76, Ah receptor
Calculated Molecular Weight 848 aa, 96 kDa
Observed Molecular Weight100 kDa
GenBank Accession NumberBC070080
Gene Symbol AHR
Gene ID (NCBI) 196
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP35869
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter. AHR calculated molecular masses differ by <10%, compared with the apparent molecular masses predicted from SDS-PAGE for the two receptors (105 and 95 kDa, respectively). (PMID: 8246913)