验证数据展示
产品信息
68237-1-PBS targets ALDH2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Rabbit, Pig samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | Human, Mouse, Rat, Rabbit, Pig |
Immunogen | ALDH2 fusion protein Ag7463 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | aldehyde dehydrogenase 2 family (mitochondrial) |
Synonyms | ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM |
Calculated Molecular Weight | 56 kDa |
Observed Molecular Weight | 50-55 kDa |
GenBank Accession Number | BC002967 |
Gene Symbol | ALDH2 |
Gene ID (NCBI) | 217 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P05091 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.