验证数据展示
产品信息
68396-1-PBS targets ALDOB in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat, rabbit |
免疫原 | ALDOB fusion protein Ag12823 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | aldolase B, fructose-bisphosphate |
别名 | ALDB, ALDOB, Liver type aldolase |
计算分子量 | 316 aa, 35 kDa |
观测分子量 | 35-40 kDa |
GenBank蛋白编号 | BC029399 |
基因名称 | ALDOB |
Gene ID (NCBI) | 229 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P05062 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Fructose-1,6-bisphosphate aldolase is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.Vertebrates have 3 aldolase isozymes, aldolase A (ALDOA), B (ALDOB), and C (ALDOC). Deficiency of this enzyme ALDOB causes an accumulation of fructose-1-phosphate after fructose intake, which results in toxic symptoms like vomiting, hypoglycemia, jaundice, elevated liver enzymes and hepatomegaly(PMID:22375183). This antibody may detect ALDOA.