验证数据展示
产品信息
16454-1-PBS targets AP3D1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | AP3D1 fusion protein Ag9390 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | adaptor-related protein complex 3, delta 1 subunit |
别名 | |
计算分子量 | 1153 aa, 130 kDa |
观测分子量 | 110 kDa |
GenBank蛋白编号 | BC010065 |
基因名称 | AP3D1 |
Gene ID (NCBI) | 8943 |
RRID | AB_10596951 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O14617 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP3D1 is a subunit of the AP-3 complex which is composed of two large adaptins (AP3D1 and AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP-3 complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.