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APLP2 Recombinant antibody

APLP2 Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241655G7

Cat no : 84703-3-RR

Print datasheet

Synonyms

Amyloid-like protein 2, Amyloid like protein 2, Amyloid beta precursor like protein 2, Amyloid beta, A4

验证数据展示

  • WB analysis using 84703-3-RR

    WB analysis using 84703-3-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 84703-3-RR (APLP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 84703-3-RR

    Affinity and Kinetic Characterization of 84703-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84703-3-RR against Human APLP2 were performed. The affinity constant is 0.675 nM.

经过测试的应用

Positive WB detected inrat brain tissue, mouse brain tissue, SH-SY5Y cells, HEK-293 cells
Planning an IHC experiment? We recommend our IHCeasy APLP2 Ready-To-Use IHC Kit. APLP2 primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84703-3-RR targets APLP2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen APLP2 fusion protein Ag6842 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name amyloid beta (A4) precursor-like protein 2
Synonyms Amyloid-like protein 2, Amyloid like protein 2, Amyloid beta precursor like protein 2, Amyloid beta, A4
Calculated Molecular Weight 87 kDa
Observed Molecular Weight95-120 kDa
GenBank Accession NumberBC000373
Gene Symbol APLP2
Gene ID (NCBI) 334
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ06481
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Amyloid precursor-like protein-2 (APLP2) is a member of the APP (amyloid precursor protein) family including APP, APLP1, and APLP2. APLP2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. APLP2 has been shown to regulate multiple cellular functions such as neurite outgrowth, axogenesis, corneal epithelial wound healing, cell adhesion, migration, and mitosis. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. APLP2 has been implicated in the pathogenesis of Alzheimer's disease.

实验方案

Product Specific Protocols
WB protocol for APLP2 antibody 84703-3-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols