验证数据展示
产品信息
66739-1-PBS targets ARL13B in WB, IF/ICC, IF-Fro, Indirect ELISA applications and shows reactivity with human, mouse, pig, canine samples.
经测试应用 | WB, IF/ICC, IF-Fro, Indirect ELISA Application Description |
经测试反应性 | human, mouse, pig, canine |
免疫原 | ARL13B fusion protein Ag12031 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ADP-ribosylation factor-like 13B |
别名 | ARL2-like protein 1, ARL2L1, ARL2 like protein 1, ADP-ribosylation factor-like protein 2-like 1, ADP-ribosylation factor-like protein 13B |
计算分子量 | 48 kDa |
观测分子量 | 60 kDa |
GenBank蛋白编号 | BC094725 |
基因名称 | ARL13B |
Gene ID (NCBI) | 200894 |
RRID | AB_2882088 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q3SXY8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).